Antiviral antifungal therapy Flashcards

1
Q

Antiviral ziduvudind

A

Cellular thymodine kinase inhibits rna dependant dna polymerase, in corporated into viral dna termination

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2
Q

Antiviralq acylvoir

A

Activation by enzyme thymidine kinase

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3
Q

Antifungal amphoterin B lipophillic

A

Ergosterol binding, poor absorbtion alters permeability

Slow intravenous with iodine

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4
Q

Azoles

A

Fluconazole, oral plus intravenous

Ketokonazole: shampp

Moa: inhibit firmation of ergosterol, inhibit fungal cytochrome P450

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