Antiviral antifungal therapy Flashcards
1
Q
Antiviral ziduvudind
A
Cellular thymodine kinase inhibits rna dependant dna polymerase, in corporated into viral dna termination
2
Q
Antiviralq acylvoir
A
Activation by enzyme thymidine kinase
3
Q
Antifungal amphoterin B lipophillic
A
Ergosterol binding, poor absorbtion alters permeability
Slow intravenous with iodine
4
Q
Azoles
A
Fluconazole, oral plus intravenous
Ketokonazole: shampp
Moa: inhibit firmation of ergosterol, inhibit fungal cytochrome P450