Antiviral Agents Flashcards

1
Q

Influenza

A

Target: Inhibiton of viral Neuraminidase

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2
Q

Influenza

Pharmakinetics of medications

A
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3
Q

Influenza

Medications clinical use

A

Adverse reactions

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4
Q

Influenza

Inhibition of uncoating

A

Amantadine - Rimantadine

Clinical Uses - Prophylaxis and treatment of influenza A infections – NO current use due to resistance

Adverse Reactions

  • Amantadine may cause insomnia, concentration difficulty, lightheadedness / dizziness, headache
  • Rimantadine better tolerated - poor CNS penetration
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5
Q

Herpes Virus (HSV 1 and 2)

A
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6
Q

Mechanism of actions of acyclovir and analogs:

A

Resistance:

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7
Q

Pharmacokinetics

A
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8
Q

Clinical uses in HSV 1 and 2

A
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9
Q

Clinical considerations

A

Varizella Zolster

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10
Q
A
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11
Q
A
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12
Q
A
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13
Q

Cytomegalovirus

A
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14
Q

Samples cases

A
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15
Q
A
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