Antipsycotics

Question 1

Chlorpromazine

Answer 1

Typical. Low-Moderate potency

SE:poikilothermia, Sedation, Hypotension, Seizure threshold reduction, ECG

Question 2

Fluphenazine

Answer 2

Typical. High Potency, ECG, EPS

Question 3

Haloperidol

Answer 3

Typical. High Potency, ECG, EPS

Question 4

Aripiprazole

Answer 4

Atypical

Question 5

Clozapine

Answer 5

Atypical
SE: Agranulocytosis* (monitor WBC), Sedation, Muscarinic/Cholinergic, Metabolic effects (Hyperglycemia/Hyperlipidemia), Seizure threshold reduction, Weight gain, hypotension*

Does NOT cause ECG changes or stroke

Question 6

Olanzapine

Answer 6

Atypical
SE: Stroke, weight gain (Oompalumpa), Muscarinic/Cholinergic*, Metabolic effects (Hyperglycemia/Hyperlipidemia), Seizure threshold reduction

Question 7

Paliperidone

Answer 7

Atypical

SE: Stroke, ECG changes,EPS

Question 8

Quetiapine

Answer 8

Atypical

SE: Sedation*

Question 9

Risperidone

Answer 9

Atypical

SE: Stroke, Hyperprolactinemia, Hypotension,EPS

Question 10

Ziprasidone

Answer 10

Atypical

SE:ECG changes*

Question 11

Muscarine side effects

Answer 11

Dry mouth, constipation, urinary retention, blurred vision, sedation

Question 12

Alpha-adrenergic side effects

Answer 12

Orthostatic hypotension, Impotency/Ejaculation interference

Question 13

Neuroleptic Malignant Syndrome antidote

Answer 13

Dantrolene
Fatal, severe Parkinsons like movement disorder
-catatonia, autonomic instability, stupor

Question 14

All Typical Agents have what side effects?

Answer 14

Hyperprolactinemia, Neuroleptic Malignant Syndrome (injectable, high potency class)

Question 15

All atypical Agents have what SE?

Answer 15

Weight gain, Metabolic (hyperglycemia, hyperlipidemia), death in elderly demented, ECG changes, stroke