antipsychotic facts

Question 1

Rx potentially inappropriate in elderly (STOPP criteria) in pt with parkinsonism or Lewy Body Disease due to risk of severe extrapyramidal symptoms unless the following 2 are given

Answer 1

quetiapine
clozapine

Question 2

2 most likely to cause postural hyotension

Answer 2

quetiapine
clozapine

Question 3

monitoring of pt parameters for all antipyschotics - advisable to measure the following

Answer 3

advisable to measure prolactin at start, 6 months, yearly

Question 4

how often do pt with schizo need to have physical health monitoring including CVD risk assessment

Answer 4

atleast annually

Question 5

2 most likely to cause weight gain

Answer 5

olanzapine
clozapine

Question 6

Which antipsychoitcs are licensed in UK for treating non cognitive symptoms of dementia

Answer 6

Haloperidol and risperidone are the only antipsychotics licensed in the UK for treating non-cognitive symptoms of dementia.

Question 7

3 important SE of clozapine

Answer 7

neutropenia and agranulocytosis
myocarditis and cardiomyopathy
intestinal obstruction

Question 8

high risk of relapse when antipsychoitcs are stopped after…

Answer 8

There is a high risk of relapse if medication is stopped after 1–2 years