Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology > Antiprotozoal drugs > Flashcards

Antiprotozoal drugs Flashcards

1
Q

Which mosquito transfers Malaria?

A

Anopheles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What organism is the most dangerous that transfers Malaria?

A

Plasmodium Falciparum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the first option for Malaria prophylaxis?

A

Chloroquine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What do we use if area has chloroquine-resistant strains of P.falciparum?

A

Doxycycline (If they cant tolerate mefloquine)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What do we use if Malaria illness is already severe?

A

Quinine/Quinidine parenterally and IV artesunate if Q is not available

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

When is Mefloquine effective against Falciparum and Vivax?

A

When they are in their asexual blood forms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

How are Mefloquine and Chloroquine and Primaquine affected by CYP enzymes?

A

They are major substrates for specific CYP enzymes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is a side effect of Mefloquine?

A

Neuropsychiatric effects, contraindicated for crazy patients

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

When is Primaquine active?

A

Against exoerythrocytic stages

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

When is Primaquine indicated?

A

For the ultimate cure of Vivax malaria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

When do we use Tafenoquine?

A

Maybe if the Parasite is not in the exoerythrocytic stage and we cant use Mefloquine and we use it to treat acute P.vivax

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What do we use with Tafenoquine?

A

Organic Cation Transporter to keep plasma levels raised

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Tafenoquine side effects?

A

Anemia and other blood disorders or psychiatric effects like Mefloquine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

When do we use Artesunate?

A

It can work for all stages and only used in severe P.falciparum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is a sign of Entamoeba histolytica infection?

A

Bloody diarrhea and stomach pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What drug do we use for Amebiasis infections?

A

Metronidazole

17
Q

What are some side effects of Metronidazole?

A

Flat T wave on ECG, headache, metallic taste, nausea, genital infections

18
Q

What to avoid while on Metronidazole?

A

Alcohol because it can make symptoms bad

19
Q

What is the most common anti-helminthic drug? With a broad spectrum?

A

Mebendazole

20
Q

What is the MOA of Mebendazole?

A

Irreversibly prevents glucose uptake for parasites

21
Q

What is a side effect of Mebendazole?

A

Hepatotoxic

22
Q

What to avoid while on Mebendazole?

A

Metronidazole (Amebiasis drug)

23
Q

What drug do we use for Tania solium?

A

Albendazole

24
Q

What is a substitute for Mebendazole if someone has liver problems?

A

Albendazole but it can cause headaches

25
Q

What does pyrantel pamoate do?

A

It paralyzes the helminth using acetylcholine

26
Q

What organism do we use pyrantel pamoate for?

A

Enterobius vermicularis

27
Q

What is the first drug choice for lice?

A

Permethrin

28
Q

What are the second drug choices for lice?

A

Malathion and Benzyl alcohol

Pharmacology (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions