Antiphospholipid Antibody Syndrome Flashcards
1
Q
What is APS?
A
An acquired disorder that appears are recurrent arterial thrombosis or fetal loss in women
2
Q
Labs
A
IgA aCL and anti B2-glycoprotein 1
3
Q
Nephropathic features?
A
Thrombosis
4
Q
Most common skin manifestations?
A
Livedo reticularis and skin ulcers
5
Q
What are the musculoskeletal manifestations?
A
Necrosis of bones and metatarsal fracture of the spine and ribs
6
Q
What if there’s aPL present, but no thrombosis or clinical events?
A
Then it’s NOT enough to diagnose APS syndrome
7
Q
What is the best predictor for aPL?
A
Positive LA (lupus anticoagulant)
8
Q
Treatment
A
Heparin warfarin aspirin
