Ankylosing Spondylitis

Question 1

What is SPA

Answer 1

Inflammatory arthropathies affecting the mainly spine and show signs in extra-articular sites

Question 2

Since PSA is genetic, what molecule is the cause

Answer 2

HLA-B27

Question 3

Rheumatology manifestations

Answer 3

Enthesitis, Peripheral arthritis

Question 4

Specific manifestations

Answer 4

Psoriasis and IBD

Question 5

What is Enthesitis

Answer 5

Tendon and ligament pain

Question 6

When is Enthesitis pain at its worst

Answer 6

Morning

Question 7

Median age group for AS?

Answer 7

Younger adults

Question 8

Biggest sign of AS?

Answer 8

Lower back pain

Question 9

So what makes the lower back pain specific to AS?

Answer 9

More than 3 months, morning stiffness, before 40years old

Question 10

Physical AS findings?

Answer 10

Restricted spine movement, bad posture, sacroillitis

Question 11

Commonest places to find Enthesitis?

Answer 11

Achilles and Costochondral regions

Question 12

Patients are radiographed for their sacroillitis, that’s then graded based on the New York grading system, what’s that?

Answer 12

Grade 1 suspicious, grade 4 total ankylosis

Question 13

What do the X rays show?

Answer 13

Bamboo spine and shiny corners

Question 14

How do we best visualize Enthesitis?

Answer 14

MRI or US

Question 15

How to diagnose?

Answer 15

Sacroiliitis, back pain >3months, limited lumbar mobility

Question 16

Goal of Treatment

Answer 16

No cure, only supportive

Question 17

Treatmemt regimen

Answer 17

NSAIDS and corticosteroids

Question 18

When should we do surgery?

Answer 18

Hip replacement