Antiparkinsonian Drugs Flashcards
1
Q
Dopamine precursors
A
Levodopa
2
Q
COMT inhibitors
A
1-Tolcapone
2- Entacapone
3
Q
Selective MAO-B inhibitors
A
Selegiline
4
Q
Selective MAO-B inhibitors
A
Selegiline
5
Q
Dopamine agonists
A
Bromocriptine
6
Q
Release of dopamine and inhibition of its reuptake
A
Amantadine
7
Q
Peripheral decarboxylation can be minimized by administration of a decarboxylase inhibitor which can’t cross BBB
A
1-carbidopa
2- benserazide.
8
Q
Adverse effects of COMT inhibitors
A
fulminating hepatic necrosis
9
Q
Adverse effects of Selegiline
A
Insomnia
10
Q
Adverse effects of Amantadine
A
Skin pigmentation
11
Q
Anticholinergic drugs
A
1-Benztropine
2– Orphenadrine
3– Trihexyphenidyl
12
Q
Anticholinergic drugs contraindicated with
A
1-prostatic hypertrophy
2- narrow-angle glaucoma
3-there is some degree of dementia
