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Pharmacology > Antimuscarinics > Flashcards

Antimuscarinics Flashcards

0
Q

Ganglionic blockers

A

Trimethophan (Arfonad)

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1
Q

Antimuscarinic

A 
Atropine
Glycopyrrolate (Robinul)
Benzotropine (Cogentin)
Propantheline
Scopolamine
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2
Q

Neuromuscular Blockers

A

Nondepolarizing: vecuronium, cisatracurium (Nimbex), pancuronium (Pavulon), rocuronium (zemuron)

Depolarizing: succinylcholine (Anectine)

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3
Q

Atropine sulfate adult dose

A

0.4 - 1.0mg

For bradycardia repeat 3-5minutes up to 3 times

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4
Q

Robinul injection

A

0.2-0.6mg

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5
Q

Effects of Ganglionic blockers

A

Profound hypotension is loss of sympathetic tone vasculature and histamine release
Negative chronotrope, negative ionotrope
Profound constipation

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6
Q

Ganglionic blockers

A

Trimethophan (Arfonad)

Dose: 1.0-3.0mg bolus
0.5-6.0mg/min

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7
Q

Nondepolarizing neuromuscular blocker drug interactions

A

Antagonized by acetylcholinesterase inhibitors
Synergistic with Ca channel blockers
Synergistic with halogenated hydrocarbon gas anesthetics
Aminoglycoside antibiotics also inhibit ACh release and therefore synergistic

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8
Q

Anectine (SUX)

A

200mg/10mL

Very short acting , used for intubation

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Pharmacology (9 decks)

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