Antimicrobials Flashcards
Name the beta-lactams
Penicillins
Cephalosporins
Carbapenems
What is the mechanism of action of Vancomycin?
Inhibits cell wall synthesis
How do flouroquinolones and rifamycins work?
Inhibit nucleic acid synthesis
How do trimethoprim and sulfonamides work?
Stop metabolite production
How does Daptomycin work?
Inhibits cell MEMBRANE synthesis
What class does Gentomycin belong to?
Aminoglycosides - inhibit protein synthesis
Why are Clavulanic acid and Amoxicillin co-prescribed as Co-Amoxiclav?
They have a synergistic effect
Clavulanic acid inhibits the effect of some beta lac tamas ever enzymes so amoxicillin can work better
On what part of the bacteria cel does Amoxicillin work?
Acts on the cell wall
What are the 5 I’s of antimicrobial stewardship?
Identify Isolate Investigate Inform Initiate treatment
What is the ABCDEF of Identify in the 5 I’s of antimicrobial stewardship?
Abroad Blood borne virus Colonised Diarrhoea and vomiting Expectorating Funny looking rash
What can be prescribed for the treatment of herpes simplex virus?
Acyclovir