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Infectious Diseases > Antimicrobials > Flashcards

Antimicrobials Flashcards

1
Q

flucloxacillin contraindications / precautions

A

hx of cholestatic hepatitis with dicloxacillin or flucloxacillin

sodium restriction

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2
Q

Se of flucloxacillin

A

Common: transinet LFT derangement

rareL cholestatic hepatitis esp >55, females >2/52

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3
Q

Gentamicin precautions, 4

A
  1. neuromuscular disease
  2. hypoclacemia, hyperMg, Ga, citrated blood transfusion: increased risk of NM ADRs
  3. ototoxicity
  4. renal impairment
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4
Q

SEs of gentamicin

A
  1. nephro
    >7-10/7, increasing serum Cr and proteinuria, acute tubular necrosis may occur
  2. ototoxicity 50% reversible
    Rare
  3. neuromuscular blockade
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5
Q

rx for gentamicin-induced neuromuscular blockade (presents as respi depression)

A

IV calcium gluconate

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6
Q
A
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Infectious Diseases (17 decks)

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