Antimicrobials Flashcards
1
Q
daptomycin MOA
A
depolarization
2
Q
daptomycin contraindications
A
pneumonia
(inactivated by surfactant)
3
Q
aztreonam indications
A
Gm- aerobes
(pseudomonas)
4
Q
cilastin
A
prevents inactivation of imipenem
5
Q
carbapenem indications
A
Gm- infections (caused by empirical Tx resistant bacteria)
6
Q
chloramphenicol relevance
A
meningitis (developing countries)
7
Q
griseofulvin MOA
A
bind microtubules to prevent division
8
Q
terbinafine relevance
A
dermatophyte infection
9
Q
___ inhibits squalene epoxidase
A
terbinafine
10
Q
___ block glucan synthesis
A
echinocandins
11
Q
IV echinocandin relevance
A
systemic candidiasis
12
Q
-pravir
A
NS3/4A protease inhibitor
(HCV)
13
Q
-asvir
A
NS5A protease inhibitor
(HCV)
14
Q
-buvir
A
NS5B protease inhibitor
(HCV)
15
Q
gancyclovir MOA
A
same as acyclovir
(needs phosphorylated to function)
