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Pharmacology > Antimicrobial Agents > Flashcards

Antimicrobial Agents Flashcards

1
Q

Ampicillin

A 
PO IV IM 
B lactam (aminopenicillin)
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2
Q

Amoxicillin

A 
PO
B lactam (aminopenicillin)
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3
Q

Piperacillin

A 
IV
B lactam (anti-pseudomonal penicillin)
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4
Q

Ceftraixone

A

IV IM

3rd gen cephalosporin

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5
Q

Ceftazidime

A

IV IM

3rd gen cephalosporin

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6
Q

Cefepime

A

IV IM

4th gen cephalosporin

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7
Q

Meropenem

A

IV

carbapenem

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8
Q

Ertapenem

A

IV IM

carbapenem

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9
Q

Ampicillin-sulbactam

A

IV

B lactamase inhibitor

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10
Q

Amoxicillin-clavulanic acid

A

PO

B lactamase inhibitor

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11
Q

Piperacillin-tazobactam

A

IV

B lactamase inhibitor

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12
Q

Vancomycin

A

PO IV

glycopeptide

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13
Q

Ciprofloxacin

A

PO IV topical

fluoroquinolones (FQ)

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14
Q

Levofloxacin

A

PO IV topical

FQ

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15
Q

Gentamicin

A

IV IM topical

Aminoglycoside

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16
Q

Moxifloxacin

A

PO IV topical

FQ

17
Q

Doxycycline

A

PO IV

tetracycline/glycylcycline

18
Q

Azithromycin

A

PO IV topical
“Z-pak”
macrolide/ketolide

19
Q

Clindamycin

A

PO IV IM topical

lincosamide

20
Q

Linezolid

A

PO IV

oxazolidinone

21
Q

Oseltamivir

A

PO

antiviral

22
Q

Fluconazole

A

PO IV

antifungal

23
Q

Itraconazole

A

PO IV

antifungal

24
Q

Voriconazole

A

PO IV

antifungal

25
Q

Penicillins

A

MOA: inhibits the transpeptidation rxn (last step in peptidoglycan sythesis) –> inhibits cell wall synthesis

26
Q

Cephalosporins

A

MOA: inhibits the transpeptidation rxn (last step in peptidoglycan sythesis) –> inhibits cell wall synthesis
1st gen = good GPB coverage, modest GNB coverage
2nd gen = good GNB coverage
3rd gen = best GNB coverage (esp Enterobacteriae)
4th gen = biggest spectrum, used in serious infxns

27
Q

Carbapenems

A

MOA: inhibits the transpeptidation rxn (last step in peptidoglycan sythesis) –> inhibits cell wall synthesis

28
Q

B lactamase inhibitors

A

MOA: inhibits B lactamases so B lactams can stop cell wall synthesis

29
Q

Fluoroquinolones (FQ)

A

MOA: targets bacterial DNA gyrase and topoisomerase –> stops DNA replicaiton and transcription

30
Q

Glycopeptides

A

MOA: inhibits cell wall synthesis by binding D-Ala-D-Ala terminal section of cell wall precursor units

31
Q

Aminoglycoside

A

MOA: binds 30S ribosome –> stops protein synthesis

32
Q

Macrolides/ketolides

A

MOA: binds 50S ribosome –> stops protein synthesis

33
Q

Lincosamides

A

MOA: binds 50S ribosome –> stops protein synthesis

34
Q

Oxazolidinones

A

MOA: binds 50S ribosome –> stops protein synthesis

35
Q

Tetracyclines/Glycylcyclines

A

MOA: binds 30S ribosome –> stops protein synthesis

Pharmacology (7 decks)

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