Antimanic, antipsychotics and anxiolytics Flashcards
What drugs are used in the treatment of mania
Lithium
Anticonvulsants
Atypical antipsychotics
What anticonvulsants are used in the treatment of mania
carbamazepine
lamotrigine
valproic acid
What are first generation anti-psychotics
Haloperidol (haldol)
Fluphenazine
What are second generation antipsychotics
olanzapine
risperidone
lurasidone
ziprasidone
quetipaine
ariprprazole
What are the side effects of antipsychotic medications
psudodepression
drowsiness
extrapyramidal reactions
neuroleptic malignant syndrome
anti-muscarinic effects
weight gain
agranulocytosis (clozapine)
QT prolongation
What are common AE of lithium
Tremor (m/c - can be treated w/ propranolol)
choreoathetosis, hyperactivity, ataxia, dysarthria
marked mental confusion
decrease thyroid function
nephrogenic DI
edema
‘sick-sinus’ syndrome
What antimanic/antipsychotic medications need monitoring
Lithium: concentrations to assess dosage requirements
Clozapine: risk of agranulocytosis
What are the benzodiazepines
Diazepam
clonazepam
lorazepam
temazepam
alprazolam
flumazenil (full agonist)
What are the AE of Benzos
sedation
ataxia/falls
impaired motor perforamance
anterograde amnesia
disinhibition of impulses
what is the treatment of benzo OD
flumazenil
What are the non-benzo GABA agnoist hypnotics
Zolpidem (ambien)
- high TI unless combo with other CNS depressants
- has abuse potential
What are the non-GABA anxiolytics
Antidepressants (TCAs, MAOIs, SSRI)
Trazodone
Mirtazapine
Buspirone
Propranolol
What medication classes can be used to treat GAD
SSRI (citalopram)
SNRI (venlafaxine)
Buspirone
Benzos
What medication classes can be used to treat phobias
Benzos (acutely)
TCAs
MAOIs (prevention)
What medication classes are used to treat panic disorders?
Benzos (acute)
TCAs
MAOIs (prevention)
