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Farmaco - Respiratorio > Antiinflamatorios de uso respiratorio > Flashcards

Antiinflamatorios de uso respiratorio Flashcards

1
Q

Se divide en 2

A

Antileucotrienos
Glucocorticoides

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2
Q

Antileucotrienos

A

Productos del acido araquidonico
Serie 4 (LTA4, LTB4, LTC4, LTD4, LTE4)
Inflamación
LTC4, LTD4 y LTE4: broncoconstriccion, aumento de secreciones traqueobronquiales, disminucion aclaramiento mucociliar, aumento permeabilidad capilar

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3
Q

Antileucotrienos

A

Inhibicion de la union de leucotrienos al receptor cistenil leucotrieno
Impide la union de los LTC4, LTD4 y LTE4 a su receptor, evita acciones broncoconstrictoras

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4
Q

Antileucotrienos

A

Montelukast
Zafirlukast
Pranlukast

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5
Q

Antileucotrienos - Efectos

A

Disminuye la broncoconstriccion
Reduce la inflamacion de las vias aereas (linfocitos, macrofagos y basofilos en alveolos)
Previene el espasmo bronquial - aspirina
Atenua la respuesta ante los alergenos
Reduce las exacerbaciones del asma

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6
Q

Antileucotrienos - RAM

A

Sindrome Churg - Strauss (vasculitis granulomatosa)
Cefalea
Somnolencia
Fiebre
Dolor abdominal
Dispepsia
Congestion nasal

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7
Q

Glucocorticoides

A

Ciclesonida
Budesonida
Beclometasona
Fluticasona

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Farmaco - Respiratorio (6 decks)

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