Antihypertensive Flashcards

1
Q

can beta-blockers be abruptly stopped?

A

no

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2
Q

what do diuretics end in?

A

-zone, -ide, -thiazide

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3
Q

what are alpha and beta blockades used for?

A
  • HTN
  • HF
  • cardiomyopathy
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4
Q

what is the place of action of ace inhibitors?

A

kidneys

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5
Q

what do ace inhibitors end in?

A

(-pril)

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6
Q

what is the place of action for direct renin inhibitors?

A

kidneys

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7
Q

do ace inhibitors work well on the black population?

A

no (would need a higher dose or a different drug)?

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8
Q

what is the action of ARBs?

A

works by blocking the action of angiotensin II

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9
Q

what is the use for ARBs?

A
  • HTN
  • HF
  • nephropathy
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10
Q

what is the adverse effect associated with vasodilators?

A

SLE (lupus like symptoms such joint pain and rashes)

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11
Q

can ace inhibitors be used during pregnancy?

A

no - black box warning

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12
Q

what do alpha1 adrenergic blockers typically treat?

A

BPH and lowers BP simultaneously

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13
Q

what two medication categories have the rare but serious side effect of angioedema?

A
  • ace inhibitors

- ARBs

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14
Q

is 90/60 an acceptable BP for a pt taking mixed alpha and beta blockades?

A

yes - if the pt can tolerate a lower BP is ok

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15
Q

what are the adverse effects associated with direct renin inhibitors?

A
  • dizziness
  • headache
  • diarrhea
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16
Q

what is the action of beta-adrenergic blockers?

A

block beta1 receptors in the heart

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17
Q

are alpha1 adrenergic blockers are 1st line treatment for BP?

A

no

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18
Q

what are central acting SNS inhibitors used for?

A
  • HTN
  • severe pain
  • ADHD
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19
Q

what medication category cause SLE?

A

vasodilaters

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20
Q

what education is related to calcium channel blockers?

A

do not take with grapefruit juice

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21
Q

what is the teaching needed for direct renin inhibitors?

A

don’t take with a high fat meal because of enzyme competition

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22
Q

what is the action of alpha1 adrenergic blockers?

A
  • interferes with sympathetic stimulation by blocking alpha1, directly relaxes arteriolar smooth muscle in the prostate and bladderneck
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23
Q

do beta-blockers work well in the black population?

A

no

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24
Q

what are the adverse effects of calcium channel blockers?

A
  • bradycardia

- peripheral edema related to HF

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25
Q

what is the name of the nonselective beta-blockers? what receptors do they work on? what is it used more for?

A

propanolol

  • beta 1 and 2
  • tachycardia
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26
Q

what is the place of action for ARBs?

A

kidneys

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27
Q

can ARBs inhibitors be used during pregnancy?

A

no

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28
Q

what medication would be good for someone with kidney disease and hypertension?

A
  • ace inhibitors

- ARBs

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29
Q

direct renin inhibitors are typically …

A

combined with another drug

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30
Q

are central acting SNS inhibitors ok for pregnancy?

A

no

31
Q

what is the action of central acting SNS inhibitors?

A

stimulates alpha 2 receptors into the CNS which leads to decreased of NE release (NE typically vasoconstricts but it is inhibited with helps decreases BP)

32
Q

what are direct renin inhibitors used for?

A

HTN

33
Q

what does ARBs stand for?

A

angiotensin II receptor blockers

34
Q

why do beta-blockers potentially cause bronchoconstriction?

A

nonselective beta-blockers work on beta 1 and beta 2, beta 2 is on the lungs which can cause bronchoconstriction so be careful with pts with lung disease

35
Q

what are the side effects associated with central acting SNS inhibitors?

A
  • dry mouth
  • rebound HTN
  • vivid dreams
  • behavior changes
36
Q

what medication can cause thrombocytopenia?

A

alpha and beta-blockades

37
Q

what is the benefit of diuretics treating HTN?

A

cheap and effective

38
Q

what is the name of the drug that is a direct renin inhibitor?

A

tekturna

39
Q

what are the adverse effects associated with alpha1 adrenergic blockers?

A
  • orthostatic hypotension
  • dizziness
  • abnormal ejaculation
  • nasal congestion
40
Q

what is the ending for alpha1 adrenergic blockers?

A

-osin

41
Q

what diuretic is typically the 1st line of treatment for HTN?

A

thiazide diuretics

42
Q

what is the action of mixed alpha and beta blockades?

A
  • decrease peripheral resistance

- reduces plasma renin and aldosterone levels

43
Q

To lower BP, you should always start with …

A

diet, exercise, stress management

44
Q

what is the place of the action for alpha and beta-blockades?

A

heart and kidneys

45
Q

what are the adverse effects of alpha and beta-blockades?

A
  • fatigue
  • hypotension
  • dizziness
  • thrombocytopenia
46
Q

what are calcium channel blockers used for?

A
  • HTN
  • angina
  • cardiac dysrhythmias
47
Q

are calcium channel blockers used as 1st line treatment for HTN?

A

yes

48
Q

what is the action of ace inhibitors?

A

blocks angiotensin 1 from converting angiotensin 2

49
Q

do ARBs work well on the black population?

A

no

50
Q

what is the ending for beta-blockers?

A

-olol

51
Q

vasodilators are typically used as …

A

adjunct therapy

52
Q

labetalol is an alpha and beta-blockade, what is it used for? what route?

A

used on uncontrolled BP

  • often used only in the hospital
  • given through IV multiple times a day due to short half life
53
Q

what are diuretics used to treat?

A
  • HTN
  • HF
  • edema
54
Q

what two medication categories can treat nephropathy?

A
  • ace inhibitors

- ARBs

55
Q

you should be aware of what with beta-blockers?

A

blood sugar

56
Q

what are the adverse effects associated with beta-blockers?

A
  • bradycardia
  • HF
  • bronchoconstriction
  • fatigue
  • dizziness
57
Q

what are the adverse effects of diuretics?

A
  • frequent urination

- loss of electrolytes (K+, NA+, and Cl+)

58
Q

what is the name of the cardioselective beta-blockers? what receptors do they work on?

A

metoprolol and atenolol

- block only beta 1

59
Q

what is the action of calcium channel blockers?

A

inhibits calcium movement into contractile myocardial cells

  • slows conduction through AV & SA nodes which decreases HR
  • dilate peripheral arteries
  • decrease peripheral resistance
60
Q

what are ace inhibitors used for?

A
  • HTN
  • HF
  • MI
  • nephropathy
61
Q

what medication can grapefruit juice not be taken with?

A

calcium channel blockers

62
Q

are calcium channel blockers good for the black population?

A

yes

63
Q

what are beta-blockers used for?

A
  • HTN
  • tachycardia
  • angina
  • post Mi
64
Q

what do vasodilators treat?

A
  • angina

- HTN

65
Q

what is the action of diuretics?

A

reduce blood volume and arterial resistance

66
Q

coreg is an alpha and beta-blockade, what is it used for?

A

HF

67
Q

what is the action of vasodilators?

A

relax arteriolar smooth muscle leading to arteriolar dilation and a decrease peripheral resistance

68
Q

what are the adverse effects associated with ARBs?

A
  • angioedema
  • dizziness
  • muscle cramps
  • heart burn
69
Q

are direct renin inhibitors safe for pregnancy?

A

no

70
Q

what is the action of direct renin inhibitors?

A

inhibits the conversation of angiotensinogen to angiotensin 1

71
Q

what are the adverse effects of ace inhibitors?

A
  • angioedema
  • cough
  • increased potassium
  • first dose hypotension
72
Q

what are the types of beta-blockers?

A
  • nonselective

- cardioslecetive

73
Q

what ending do ARBS end in?

A

-sartan