Antigens and Phagocytosis Flashcards
What are Antigens?
Chemical markers, a protein found on the outside of cells that triggers an immune response
What are self and non self antigens?
Self antigens are antigens that your body recognises
Non self antigens are antigens that your body doesn’t recognise as its foreign
Where are phagocytes made?
In the bone marrow
What are Neutrophils?
They engluf and digest pathogens
What are Macrophages?
They can punch holes in the bacteria or stick proteins to the outside of the bacteria to make the more appealing for the Neutrophils to destroy
What is Phagocytosis?
Cellular process of engulfing solid particles using the cell membrane
What is the first step o Phagocytosis?
Pathogen is recognised by having a non self antigens. Pathogen attaches to the phagocytes by surface receptors
What is the second step of Phagocytosis?
The pathogen is engulfed by the phagocytes by endocytosis forming a phagosome
What is the third step of Phagocytosis?
Lysosomes fuse to phagosome to form a phagolysosome and release H2O2, HCL and digestive enzymes into phagosome to digest pathogen
What is the fourth step of Phagocytosis?
Harmless products removed by exocytosis