Antigen Recognition and Activation of the Adaptive Immune System II

Question 1

Compare and contrast the structures, antigen-binding characteristics and functions of the B cell antigen receptor (antibody) and T cell antigen receptor (TCR).

Answer 1

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Question 2

Distinguish the roles of membrane-bound and soluble antibodies in the immune response.

Answer 2

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Question 3

Explain the steps of a T cell response to antigen including the general features of T cell activation and the concepts of costimulatory signaling, clonal expansion and differentiation of effector and memory T cells.

Answer 3

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Question 4

Distinguish between T cell-dependent and T-cell independent antibody responses.

Answer 4

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Question 5

Explain the steps of a T cell-dependent antibody response including the general features of B cell activation and the concepts of T cell help, clonal expansion, isotype switching and affinity maturation.

Answer 5

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Question 6

Describe the general roles of CD4+ helper T cells, CD8+ cytotoxic T cells, plasma cells and memory B and T cells.

Answer 6

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