antifungals Flashcards

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1
Q

2 Polyenes -POLYAR OPPOSITES

A

Amphotericin B – Nystatin

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2
Q

max dose for Ampho B

A

1.5mg/kg

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3
Q

Ambisome dose

A

3-5mg/kg

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4
Q

Amphotercin acute reactions

A

fever, shaking, chills, nausea, vomiting, diarrhea, tachypnea, headache

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5
Q

Amphotericin Warnings

A

Anaphylaxis - initial dose acute reaction

Leukoencephalopathy

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6
Q

Amphotericin drug interactions

A

Imidazole
Nephrotic agents
Steroids
Chemo

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7
Q

3 Triazoles

A

FLUITRAVORI

Fluconazole - yeast, wide bioavailability
Itraconazole - broad spectrum
Voriconazole - broad spectrum- DOC for Aspergillosis
Posiconazole Broadest**

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8
Q

3 Imidazoles

A

Ketoconazole

Butoconazole

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9
Q

Toe fungus

A

Efinaconazole (jublia)

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10
Q

EXTREME ANTIFUNGAL, USED W AMPHO

A

Flucystosine - chemo like ADRs

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