Antifungals Flashcards
1
Q
Azoles
A
active against yeasts +/-molds
–Inhibit cell-membrane synthesis
–Fluconazole or clotrimazole used to treat Candida
•Itra/vori/posaconazole also active against Aspergillus
2
Q
Polyenes
A
Nystatin and Amphotericin
–Inhibit cell membrane function
–Nystatin for topical treatment of candida
–Amphotericin for IV treatment of systemic fungal infections (e.g. aspergillus) and lozenge for candida
