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GI Pharmacology > Antifungal Drugs > Flashcards

Antifungal Drugs Flashcards

1
Q

Polyene mechanism of action

A

Bind to ergosterol in cell wall

Forms aqueous pores promoting leakage

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2
Q

Imidazole and triazole mechanism of action

A

Inhibit 14 alpa- demethylase
Causes decreased ergosterol synthesis
Altering membrane fluidity

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3
Q

Terbinafine mechanism of action

A

Inhibits squalene epoxidase
Causing decreased ergosterol formation
Impairing cell wall function

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4
Q

Classes of anti-fungals

A
  • Polyenes
  • Imidazoles
  • Triazoles
  • terbinafine
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GI Pharmacology (3 decks)

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