Antiepileptic Drugs Flashcards

1
Q

What is a Barbiturate?

A

Anti epileptic and sedative hypnotic

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2
Q

What is Phenobarbitone used for?

A

Phenobarbitone is a long-acting barbiturate.

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3
Q

Define Deoxybarbiturate.

A

A type of barbiturate with a modified chemical structure.

Deoxybarbiturates are less commonly used than traditional barbiturates.

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4
Q

What is Primidone?

A

An anticonvulsant drug that is metabolized into phenobarbital.

Primidone is deoxybarbiturate

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5
Q

List two examples of Hydantoin.

A
  • Phenytoin
  • Fosphenytoin
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6
Q

What is Phenytoin primarily used for?

A

To control seizures.

Phenytoin is effective in treating tonic-clonic seizures.

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7
Q

What does Fosphenytoin convert into in the body?

A

Phenytoin.

Fosphenytoin is a prodrug of phenytoin.

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8
Q

What is Iminostilbene?

A

A class of anticonvulsant drugs, including carbamazepine.

Iminostilbenes are used for epilepsy and bipolar disorder.

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9
Q

Name two examples of iminostilbene

A
  • Oxcarbazepine
  • Carbamazepine itself

Carbamazepine is used to control seizures and mood disorders.

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10
Q

What is Succinimide?

A

A class of anticonvulsant drugs used to treat absence seizures.

Ethosuximide is a common example of a succinimide.

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11
Q

What is the primary use of Ethosuximide?

A

To treat absence seizures.

Ethosuximide is particularly effective for this type of seizure.

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12
Q

List types of Benzodiazepines.

A
  • Clonazepam
  • Diazepam
  • Lorazepam
  • Clobazam
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13
Q

What is Clobazam used for?

A

It is used as an anticonvulsant.

Clobazam is a benzodiazepine with anticonvulsant properties.

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14
Q

What is Valproate sodium also known as?

A

Valproic acid.

Valproate is used in the treatment of epilepsy and bipolar disorder.

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15
Q

What is Divalproex?

A

A formulation of valproic acid used to treat seizures and mood disorders.

Divalproex provides a delayed-release form of valproic acid.

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16
Q

What is Lamotrigine primarily used for?

A

To treat seizures and bipolar disorder.

Lamotrigine is recognized for its mood-stabilizing effects.

17
Q

Name two newer anticonvulsant drugs.

A
  • Topiramate
  • Zonisamide

Newer drugs have different mechanisms and side effect profiles compared to older drugs.

18
Q

What is Levetiracetam used for?

A

To treat seizures in epilepsy.

Levetiracetam is known for its safety and efficacy.

19
Q

What is Vigabatrin used for?

A

To treat epilepsy, particularly in patients with refractory seizures.

Vigabatrin is an irreversible inhibitor of GABA transaminase.

20
Q

What is Tiagabine’s mechanism of action?

A

Inhibits the reuptake of GABA.

Tiagabine is used for partial seizures.

21
Q

What class do Gabapentin and Pregabalin belong to?

A

Cyclic GABA analogues.

These drugs are used for neuropathic pain and seizures.

22
Q

New drugs

A

Topiramate
Zonisamide
Levetiracetam
Vigabatrin
Tiagabine
Lacosamide

23
Q

Phenyl tri azine

A

Lamo tri gine

24
Q

Anti epileptic

A

Barbiturates
Deoxybarbiturate
Hydantoin
Iminostilbene
Succinide
Aliphatic carboxylic acid
BZD
Phenyl tri axine
Cyclic GABA ANALOGUE
Newer drugs