Anti Parkinsonism Flashcards
What is an Antiparkinsonian drug?
Drugs affecting brain dopaminergic system and cholinergic system
What is a dopamine precursor used in the treatment of Parkinson’s disease?
Levodopa
Levodopa is converted to dopamine in the brain.
What are peripheral decarboxylase inhibitors?
Carbidopa, Benserazide
These inhibitors help prevent the conversion of levodopa to dopamine outside the brain.
Name a class of drugs that act as dopaminergic agonists.
Bromocriptine, Ropinirole, Pramipexole
.
What are MAO-B inhibitors?
Selegiline, Rasagiline
These drugs inhibit the enzyme monoamine oxidase B, which breaks down dopamine.
What are COMT inhibitors used for?
Entacapone, Tolcapone
These drugs inhibit catechol-O-methyltransferase, which helps prolong the effect of levodopa.
What drugs affect the brain cholinergic system?
Central anticholinergics, Anti histamines
These drugs can help manage symptoms of Parkinson’s disease.
Name a central anticholinergic drug.
Trihexyphenidyl, Procyclidine, Biperiden
These drugs are used to reduce tremors and rigidity in Parkinson’s disease.
What are examples of antihistamines that can be used in Parkinson’s disease treatment?
Orphenadrine, Promethazine
These antihistamines can also have anticholinergic effects.
Dogaminergic system glutamate (NMDA RC)agonists (Dopamine facilitator)
Amantadine
Dopaminergic system
Dopamine precursor
Periphery decarboxylase inhibitors
Dominergic agonist
COMT inhibitors
Mao B inhibitors
Glutamate agonist
Cholinergic system
Central anticholinergic
Antihistamines
Cholinergic system
Central anticholinergic
Antihistamines
