Antiemetics Sem1

Question 1

Module Quiz Question

The following medications act PRIMARILY on which Receptors in the Emetic pathway:

Haloperidol

Dimenhydrinate

Ondansetron

Answer 1

Haloperidol —-> Dopamine D2

Dimenhydrinate —> Histamine H1

Ondansetron –> Serotonin 5HT2-4

Question 2

Module Quiz Question

Which of the following is true regarding construction of antiemetic regimens?

A. Vestibular etiologies may respond best to medications acting on the D2 receptors
B. If a single antiemetic is ineffective, the addition of another acting on a different receptor may be utilized
C. Medications with D2 activity are desirable second line agents especially in those with Parkinson’s
D. All choices

Answer 2

B

Question 3

Module Quiz Question:

Which of the following adverse effects are related to Dimenhydrinate’s anticholinergic effects? Select ALL that apply.

A.	CNS depression 
B.	Arrhythmia
C.	Insomnia
D.	Headache
E.	Ataxia
F.	Restlessness

Answer 3

A , B, D and E

Question 4

Module Quiz Question

Dimenhydrinate should be used with caution in those with COPD and Seizure disorders as it can exacerbate their existing conditions. TRUE or FALSE ?

Answer 4

TRUE

Question 5

Module Quiz Question:

Which of the following is true regarding the advantages and disadvantages of Olanzapine?

A. Olanzapine does not cause CNS depression
B. Olanzapine does not cause clinically relevant QT prolongation
C. Olanzapine has higher risk of extrapyramidal effects
D. Olanzapine has an extensive half life

Answer 5

B

Question 6

MODULE QUIZ QUESTION:

Which of the following is true regarding Metoclopramide?

A. Metoclopramide exhibits the same arrhythmogenic effects as other antiemetics
B. Metoclopramide effects the PO absorption of other medications
C. Metoclopramide has significant sedative properties

Answer 6

B