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MPJE + NAPLEX 2023 PREP > ANTIDOTES - PNN > Flashcards

ANTIDOTES - PNN Flashcards

1
Q

apap

A

N-acetylcysteine - acetadote (IV), Cetylev (oral)

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2
Q

anticholinergics / antihistamines

A

physostigmine (antilirium)

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3
Q

organophosphates / pesticides / malathion

A

atropine or pralidoxime (protopam, 2-pam)

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4
Q

cholinergics

A

atropine or pralidoxime (protopam, 2-pam)

atropine + pralidoxime (ATNAA, duodote)

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5
Q

cyanide

A

cyanide antidote kit, cyanokit (hydroxocobalamin)

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6
Q

hypoglycemic agents

A

glucagon

octreotide (sandostatin) also used for sulfonylureas

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7
Q

beta blockers

A

glucagon

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8
Q

calcium channel blockers

A

calcium chloride

and/or calcium glucagon

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9
Q

digitalis

A

dig immune fab

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10
Q

theophylline

A

beta blockers

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11
Q

serotonin syndrome

A

cyproheptadine

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12
Q

dystonic reaction

A

benztropine (cogentin) or diphenhydramine (benadryl)

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13
Q

NMS (neuroleptic malignant syndrome)

A

bromocriptine, dantrolene

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14
Q

ethylene glycol (antifreeze)

A

fomepizole (antizol), ethanol 10%

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15
Q

methanol (wood alcohol)

A

fomepizole (antizol), ethanol 10%

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16
Q

lead

A

dimercaprol (BAL), EDTA-Calcium, DMSA (succimer)

BAL in Oil = Dimercaprol

17
Q

arsenic

A

dimercaprol (BAL), or DMSA

BAL in Oil = Dimercaprol

18
Q

heavy metals

A

dimercaprol or penicillamine

BAL in Oil = Dimercaprol

19
Q

gold

A

dimercaprol

BAL in Oil = Dimercaprol

20
Q

mercury

A

D-penicillamine

21
Q

copper (wilson dz)

A

penicillamine

22
Q

iron (hemachromatosis disease)

A

deferoxamine (desferal)

23
Q

heparin

A

protamine sulfate

[ most of the times holding the next one or two doses will correct the situation and antidotes are rarely used ]

24
Q

warfarin

A

vitamin K (phytondione, mephyton)

[ most of the times holding the next one or two doses will correct the situation and antidotes are rarely used ]

25
Q

benzodiazepines / zolpidem

A

flumazenil (romazicon)

26
Q

opiates

A

naloxone (narcan)

27
Q

lithium

A

no antidote; correct Na+, supportive care, HD

28
Q

barbiturates

A

no antidote, use charcoal if early and alkalinize urine with NaHCO3, supportive care

29
Q

TCAs

A

NaHCO3

30
Q

dabigatran

A

idarucizumab / praxbind

31
Q

rocuronium or vecuronium

A

sugammadex (bridion)

32
Q

off-label use of acetylcysteine

A

prevention of contrast-induced nephropathy

MPJE + NAPLEX 2023 PREP (16 decks)

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