Antidotes for Overdoses Flashcards

1
Q

Antidote for Acetaminophen OD

A

N-acetylcysteine

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2
Q

Antidote for Salicylate OD

A

Na-HCO3 (sodium bicarb)

*Treat acid OD with a base

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3
Q

Antidote for Amphetamine OD

A

Cl-NH4 (ammonium chloride)

*Treat base OD with an acid

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4
Q

Antidote for Anticholinesterase / Organophosphate OD

Wet + miosis

A

Pralidoxime (antidote)

Atropine (for sx)

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5
Q

Antidote for Antimuscarinic / Anticholinergic agent OD

Dry + mydriasis

A

Physostigmine

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6
Q

Antidote for Digoxin OD

Arrhythmia +/- bradycardia

A

Anti-Dig Antibody fragments

Also K & Mg normalization

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7
Q

Antidote for Fe OD

Abd pain, hematemesis, melena, lethargy

A

Deferoxamine

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8
Q

Antidote forLead poisoning

A

Succimer (adults)
Dimercaprol (kids)
Ca EDTA (kids & adults)

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9
Q

Antidote for Arsenic, Mercury, and Gold poisoning

A

Dimercaprol or succimer

*MERCury and diMERCaprol

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10
Q

Antidote for Copper, Arsenic, and Gold poisoning

Wilson’s disease

A

Penicillamine

*“Copper Penni”

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11
Q

Antidote for Cyanide poisoning

A

Hydroxycobalamine (B12) + Thiosulfate

*Nitrites given as backup

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12
Q

Antidote for Methemoglobin poisoning

A

Methylene blue and/or Vit C

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13
Q

Antidote for CO poisoning

Flu-like, cherry red lips

A

100% O2 or Hyperbaric O2

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14
Q

Antidote for Methanol / Ethylene glycol poisoning

antifreeze

A

Fomepizole

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15
Q

Antidote for Opioid OD

Dec RR + pinpoint pupils

A

Naloxone / Naltrexone

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16
Q

Antidote for Benzodiazepine OD

A

Flumazenil + supportive

17
Q

Antidote for Tricyclic antidepressant OD

A

Na-HCO3 (sodium bicarb)

18
Q

Antidote for Heparin toxicity

A

Protamine sulfate

*Let the H in Heparin remind you of H+ (Protons like Protamine)

19
Q

Antidote for Warfarin toxicity

A

Vit K + FFP

20
Q

Antidote for t-PA / streptokinase toxicity

A

Aminocaproic acid

21
Q

Antidote for Theophylline OD

Treats asthma and causes tachycardia

A

Beta-blocker

22
Q

Antidote for Beta-blocker or Non-DHP CCB (e.g. verapamil) toxicity

A

Calcium or Glucagon or Atropine

23
Q

Antidote for Serotonin Syndrome

A

Cyproheptadine