Antidotes Flashcards

1
Q

Acetaminophen

A

N-actetylcysteine (replenishes glutathione)

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2
Q

AChE inhibitors, organophosphates

A

Atropine followed by pralidoxime

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3
Q

Amphetamines

A

NH4Cl (acidify urine) (ammonium chloride)

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4
Q

Benzodiazepines

A

flumazenil

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5
Q

Antimuscarinic, anticholinergic agents

A

physostigmine salicylate, control hyperthermia

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6
Q

beta-blockers

A

glucagon

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7
Q

carbon monoxide

A

100% O2, hyperbaric O2

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8
Q

copper, arsenic, gold

A

Penicillamine

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9
Q

cyanide

A

nitrite + thiosulfate, hydroxocobalamin

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10
Q

digitalis

A

anti-dig Fab fragments

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11
Q

heparin

A

protamine sulfate

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12
Q

iron

A

Deferoxamine, deferasirox

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13
Q

lead

A

EDTA, dimercaprol, succimer, penicillamine

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14
Q

mercury, arsenic, gold

A

Dimercaprol (BAL), succimer

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15
Q

Methanol, ethylene glycol

A

fomepizole > ethanol, dialysis

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16
Q

methemoglobin

A

methylene blue, Vit C

17
Q

Opioids

A

naloxone

18
Q

Salicylates

A

NaHCO3 (alkalinize urine), dialysis

19
Q

TCAs

A

NaHCO3 (plasma alkalinization)

20
Q

tPA, streptokinase, urokinase

A

Aminocaproic acid

21
Q

Warfarin

A

Vit K, fresh frozen plasma (if active bleeding)

22
Q

Prolong QT

A

magnesium sulfate