ANTIDOTES Flashcards

1
Q

Benzodiazepine Toxicity

A

Flumanezil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Heparin Toxicity

A

Protamine Sulfate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Warfarin Toxicity

A

Vitamin K, Fresh Frozen Plasma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Warfarin’s mechanism of action

A

decreased blood clotting by blocking enzyme called Vitamin K epoxide reductase that reactivates Vitamin K

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Warfarin affects ___________ pathway.

A

extrinsic pathway

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Clotting factors affected by warfarin?

A

Clotting Factors 1972 (10, 9, 7, 2)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Alteplase, Streptokinase Toxicity

A

Aminocaproic Acid / Tranexamic Acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What does Tranexamic Acid inhibit?

A

Activation of Plasminogen

reduces amount of plasmin that can be produced, thereby slowing the amount of clot degradation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Opioid Toxicity

A

Naloxone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Cyanide (CN-) Toxicity

A

Sodium Thiosulfate

Amyl Nitrite pearls / 3 1/2 Sodium Nitrite

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Digitalis Toxicity

A

Anti dig Fab Fragments (Digi Bind)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Lead (Pb) Toxicity

A

Edetate Calcium Disodium (EDTA)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Mercury, Arsenic, Cadmium Toxicity

A

British antilewisite (BAL) a.k.a Dimercaprol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Copper Toxicity

A

Penicillamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Iron Toxicity

A

Deferroxamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Acetaminophen Toxicity

A

N-Acetylcysteine

17
Q

Cyclophopsphamide/ Ifosfamide-induced Hemorrhagic cystitis

A

Sodium 2-mercaptoethane sulfonate

18
Q

Ethylene Glycol, Anti-freeze Toxicity

A

Ethanol

19
Q

Isoniazid Toxicity

A

Pyridoxine

20
Q

Isoniazid adverse events

A

Peripheral Neuritis, Hepatotoxicity

21
Q

Organophosphate Toxicity

A

Atropine with Pralidoxime

22
Q

Lithium Toxicity

A

Sodium Polystyrene Sulfate

23
Q

Methanol Toxicity

A

Ethanol

24
Q

Halothane/ Succinylcholine Toxicity

A

Dantrolene