ANTIBIOTICS Flashcards
agent causing death to microorganism
BACTERICIDAL
agent temporarily inhibiting the growth of microorganism
BACTERIOSTATIC
MOA: Irreversibly bind PCN-binding proteins in bacterial cell wall, causing OSMOTIC rupture and death
Penicillin
DOC for Syphilis, Group A streptococci, Listeria monocytogenes, Pasteurella multocida, Actinomyces spp. and some anaerobic infections
Penicillin
IV preparation of Penicillin
DOC for most penicillin-susceptible streptococcal infections and neurosyphilis
Aqueous Penicillin
IM repository preparation of Penicillin
Alternative treatment for Neurosyphilis in combination with Probenecid
Procaine Penicillin G
long IM repository preparation of Penicillin
Benzathine Penicillin
Antibiotic used in treating Early Latent Syphilis and Late Latent Syphilis
Benzathine Penicillin
Oral preparation of Penicillin
Penicillin V
Antibiotic used in treating Group A Streptococcal Pharyngitis
Penicillin V
DOC for treatment of infections caused by susceptible Enterococcus spp., or L. monocytogenes
Ampicillin
Antibiotic with beta-lactamase inhibitor that extends its spectrum to include MSSA, Anaerobes, and many Enterobacteriaceae
Ampicillin/Sulbactam
ORAL antibiotic similar to ampicillin that is commonly used for uncomplicated sinusitis, pharyngitis, otitis media, community-acquired pneumonia and UTIs
Amoxicillin
Oral antibiotic similar to ampicillin/sulbactam that combines amoxicillin with the B-lactamase inhibitor clavulanate
Amoxicillin/Clavulanic Acid
Penicillinase-resistant synthetic Penicillins that are DOC for treating MSSA infections
Nafcillin & Oxacillin
ORAL antibiotics with spectrum of activity similar to Nafcillin and Oxacillin
(used to treat LOCALIZED skin infections)
Dicloxacillin & Cloxacillin
Extended-spectrum Penicillin with enhanced gram-negative activity as well as enterococcal activity
(generally requires coadministration of an AMINOGLYCOSIDES for treatment of serious infection)
Piperacillin
Beta-lactamase inhibitor
Sulbactam, Tazobactam
Similar spectrum and indications as Ticarcillin/Clavulanic Acid but enhanced & has activity against ampicillin-sensitive enterococci
Piperacillin/Tazobactam
This combination of drug (penicillin/b-lactamase inhibitor) with Aminoglycosides used in treatment in Pseudomonas aeruginosa or for nosocomial pneumonia
Piperacillin/Tazobactam
Combination of drug useful for INTRAABDOMINAL and complicated soft tissue infections
Has unique role in treatment of STENOTROPHOMAS infections
Ticarcillin/Clavulanic Acid
Nafcillin and Oxacillin can cause __________. (adverse effect)
HEPATITIS - monitor patients liver function tests
Ticarcillin/Clavulanic Acid can aggravate bleeding by___________>
interfering with platelet adenosine diphosphate receptors
