Antidiabetic Flashcards

1
Q

Biguanides

A

Metformin
Decrease gluconeogenesis and increase peripheral utilisation of glucose

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2
Q

Sulphonylureas

A

Gliclazide Glipizide
Augments insulin secretion from pancreatic B-cells

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3
Q

Pioglitazone

A

Reduces peripheral insulin resistance

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4
Q

GLP-1 Receptor Agonist

A

Dulaglutide Liraglutide
Augments glucose-dependent insulin secretion and slows gastric emptying

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5
Q

DPP-4 Inhibitors (Gliptins)

A

Alogliptin Linagliptin
Inhibits dipeptidylpeptidase-4 to increase insulin secretion and lower glucagon secretion

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6
Q

SGLT2 Inhibitors

A

Canagliflozin Dapagliflozin
Inhibits SGLT2 in proximal convulated tubule reducing glucose reabsorption, increasing urinary glucose extraction

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