Antidiabetic Flashcards
1
Q
Biguanides
A
Metformin
Decrease gluconeogenesis and increase peripheral utilisation of glucose
2
Q
Sulphonylureas
A
Gliclazide Glipizide
Augments insulin secretion from pancreatic B-cells
3
Q
Pioglitazone
A
Reduces peripheral insulin resistance
4
Q
GLP-1 Receptor Agonist
A
Dulaglutide Liraglutide
Augments glucose-dependent insulin secretion and slows gastric emptying
5
Q
DPP-4 Inhibitors (Gliptins)
A
Alogliptin Linagliptin
Inhibits dipeptidylpeptidase-4 to increase insulin secretion and lower glucagon secretion
6
Q
SGLT2 Inhibitors
A
Canagliflozin Dapagliflozin
Inhibits SGLT2 in proximal convulated tubule reducing glucose reabsorption, increasing urinary glucose extraction