Antidepressants_Flashcards
What are the types of Monoamine Oxidase (MAO) enzymes?
MAO-A (non-selective, targets NE, 5-HT) and MAO-B (selective for dopamine).
Name two examples of non-selective MAO inhibitors.
Phenelzine, Tranylcypromine,Isocarboxazid
Which MAO inhibitor is selective for MAO-A?
Moclobemide.
What side effect can occur from consuming tyramine while on MAO inhibitors?
Hypertension crisis.
What is the treatment for serotonin syndrome caused by antidepressants?
Cyproheptadine and stopping the causing drug.
Which TCA is used to treat nocturnal enuresis in children?
Imipramine.
What are the side effects of TCAs due to their anti-muscarinic action?
Dry mouth, urinary retention, blurred vision.
What is the prototype SSRI with the longest half-life?
Fluoxetine.
Which SSRI is commonly used for PTSD?
Sertraline.
What is the mechanism of action of SNRIs?
Inhibit serotonin and norepinephrine reuptake.
Name one atypical antidepressant used as a smoking cessation aid.
Bupropion.
Which atypical antidepressant is effective for insomnia caused by SSRIs?
Trazodone.
What mood stabilizer is considered the drug of choice for bipolar disorder?
Lithium.
What congenital anomaly is associated with lithium use during the first trimester?
Epstein anomaly.
Name 3 Anticonvulsants maintenance drugs for bipolar disorder.
Carbamazepine, Valproic acid, Lamotrigine.
