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Psychiatric Medications > antidepressants > Flashcards

antidepressants Flashcards

1
Q

What are the most popular antidepressants?

A

SSRIs

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2
Q

What are the 6 main SSRIs?

A 
Fluoxetine
Citalopram
Sertaline
Paroxetine
Escitalopram
Fluvoxamine
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3
Q

Name the 3 main SNRIs?

A

Venlafaxine
Duloxetine
Desvenlafaxine

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4
Q

What is the main 3rd type of antidepressants that works on smoking (cravings) and S.A.D?

A

Bupropion

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5
Q

What are the advantages of SSRI, SNRI?

A

Less S/Es in comparison

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6
Q

What are the older antidepressant classes

A

Tricyclics
tetracyclics
monoamine oxidase inhibitors

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7
Q

How long do antidepressants take to start working?

A

4-6 weeks

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8
Q

What are the main possible S/Es of antidepressants? (5)

A 
NV
Weight gain
Diarrhea
Sleepiness
Sexual Problems
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9
Q

What are the remote possible S/Es of antidepressants? (12)

A 
Thoughts of suicide and dying
Suicide Attempts
New or worsening depression
New or worsening anxiety
feeling agitated or restless
panic attacks
Trouble sleeping
new or worsening irritability
acting aggressively
acting on dangerous impulses
an extreme increase in activity and talking
other unusual changes in behavior or mood
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10
Q

When you combine a “triptan” medication used treat migraines and an SSRI/SNRI what can develop?

A

serotonin syndrome

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11
Q

What are the S/S of serotonin syndrome

A 
agitation
hallucinations
high temperature
unusual BP
Ataxia possibly requiring mechanical vent
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12
Q

Brand name of citalopram

A

Celexa

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13
Q

Brand name of escitalopram

A

Lexapro

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14
Q

Brand name of fluoxetine

A

Prozac

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15
Q

Brand name of fluoxamine

A

Luvox

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16
Q

Brand name of paroxetine

A

Paxil

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17
Q

Brand name of sertraline

A

Zoloft

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18
Q

Brand name of vortioxetine

A

Trintellix

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19
Q

Brand name of vilazodone

A

Viibryd

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20
Q

Bupropion brand name

A

Wellbutrin

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21
Q

What are the 3 TCAs

A

Nortriptyline (Pamelor)
Amitriptyline (Elavil)
Imipramine (Tofranil)

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22
Q

What is the brand name of nortriptyline?

A

Pamelor

23
Q

What is the brand name of amitriptyline?

A

Elavil

24
Q

What is the brand name of imipramine?

A

Tofranil

25
Q

What is the brand name of desvenlafaxine

A

Pristiq

26
Q

What is the main SNDI?

A

mirtazapine

27
Q

What does SNDI stand for?

A

serotonin-norepinephrine disinhibitor

28
Q

What is the brand name of mirtazapine

A

Remeron

29
Q

What does MAOI stand for

A

Monoamine oxidase inhibitor

30
Q

What are the 4 main MAOIs

A

Isocarboxazid (Marplan)
Phenelzine (Nardil)
Selegiline (EMSAM)
Tranylcypromine (Parnate)

31
Q

Brand name of isocarboxazid

A

Marplan

32
Q

Brand name of phenelzine

A

Nardil

33
Q

Brand name of selegiline

A

EMSAM

34
Q

Brand name of tranylcypromine

A

Parnate

35
Q

Not sure the class but what is the brand name of trazodone

A

Oleptro

36
Q

Which class of medication causes orthostatic hypertension due to the alpha one blocking which constricts cardiac muscle?

A

TCAs (MAOIs also cause Orthos)

37
Q

What class of drug blocks the breakdown of norepinephrine, dopamine, epinephrine, and serotonin in the synaptic terminals?

A

Monoamine oxidase an MAOI

38
Q

What tricyclic antidepressant is used for childhood enuresis or bedwetting

A

Clomipramine

39
Q

What three types of drugs can mimic depression

A

Oral contraceptives, levodopa, glucocorticoids

40
Q

Which diseases and deficiencies can cause depression

A

Vitamin B deficiency thyroid problem, Alzheimer’s disease, and maybe Hashimoto’s disease

41
Q

In addition to depression what else can antidepressants help with

A

Anxiety and pain

42
Q

What is the chemical name for serotonin

A

5-HT or 5-Hydroxytryptamine

43
Q

What does serotonin affect

A

There are high concentrations of serotonin in the hypothalamus, limbic system, the maDoula, and spinal cord.

44
Q

What body functions to serotonin control

A

NREM
REM
Pain perception,
emotional states

45
Q

What enzyme terminates the action of norepinephrine in the synapse

A 
There are two
#1 MAO which is monamine oxidase 
#2 COMT =which is catecholamine o-methyltransferase
46
Q

What are the atypical antidepressants

A 
Bupropion 
Duloxetine SNRI
Mirtazapine
Nefazodone
Trazodone
Venlafaxine. SNRI
47
Q

What is the brand name for venlafaxine?

A

Effexor

48
Q

What are the 10 tricyclic antidepressants or DCA’s?

A 
Amitriptyline
Amoxapine
Clomipramine
Desipramine
Doxepin
Imipramine
Maprotiline
Nortriptyline
Protriptyline
Trimipramime
49
Q

What drug besides gabapentin and Lyrica can be used to treat neuropathic pain

A

Cymbalta (duloxitine)

50
Q

What anti-depressant can lower the Seizure threshold?

A

Bupropion/Wellbutrin

51
Q

When do you use MAOIs?

A

After TCAs and SSRIs have failed

52
Q

MAOIs to grade a certain chemical in the intestines causing that chemical to enter the bloodstream and a high concentration displacing norepinephrine within the presynaptic nerve terminal. The sudden loss of norepinephrine causes acute hypertension. what is that chemical

A

Tyramine

53
Q

What are foods that contain tyramine

A

Avocados, bananas, raisins, papaya, figs, cheese, sour cream, yogurt, beer, red wine, liver, hearing, pepperoni, salami, sausage, hot dogs, baloney, yeast, chocolate, soy sauce, fava beans

Psychiatric Medications (6 decks)

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