antidepressants

Question 1

What are the most popular antidepressants?

Answer 1

SSRIs

Question 2

What are the 6 main SSRIs?

Answer 2

Fluoxetine
Citalopram
Sertaline
Paroxetine
Escitalopram
Fluvoxamine

Question 3

Name the 3 main SNRIs?

Answer 3

Venlafaxine
Duloxetine
Desvenlafaxine

Question 4

What is the main 3rd type of antidepressants that works on smoking (cravings) and S.A.D?

Answer 4

Bupropion

Question 5

What are the advantages of SSRI, SNRI?

Answer 5

Less S/Es in comparison

Question 6

What are the older antidepressant classes

Answer 6

Tricyclics
tetracyclics
monoamine oxidase inhibitors

Question 7

How long do antidepressants take to start working?

Answer 7

4-6 weeks

Question 8

What are the main possible S/Es of antidepressants? (5)

Answer 8

NV
Weight gain
Diarrhea
Sleepiness
Sexual Problems

Question 9

What are the remote possible S/Es of antidepressants? (12)

Answer 9

Thoughts of suicide and dying
Suicide Attempts
New or worsening depression
New or worsening anxiety
feeling agitated or restless
panic attacks
Trouble sleeping
new or worsening irritability
acting aggressively
acting on dangerous impulses
an extreme increase in activity and talking
other unusual changes in behavior or mood

Question 10

When you combine a “triptan” medication used treat migraines and an SSRI/SNRI what can develop?

Answer 10

serotonin syndrome

Question 11

What are the S/S of serotonin syndrome

Answer 11

agitation
hallucinations
high temperature
unusual BP
Ataxia possibly requiring mechanical vent

Question 12

Brand name of citalopram

Answer 12

Celexa

Question 13

Brand name of escitalopram

Answer 13

Lexapro

Question 14

Brand name of fluoxetine

Answer 14

Prozac

Question 15

Brand name of fluoxamine

Answer 15

Luvox

Question 16

Brand name of paroxetine

Answer 16

Paxil

Question 17

Brand name of sertraline

Answer 17

Zoloft

Question 18

Brand name of vortioxetine

Answer 18

Trintellix

Question 19

Brand name of vilazodone

Answer 19

Viibryd

Question 20

Bupropion brand name

Answer 20

Wellbutrin

Question 21

What are the 3 TCAs

Answer 21

Nortriptyline (Pamelor)
Amitriptyline (Elavil)
Imipramine (Tofranil)

Question 22

What is the brand name of nortriptyline?

Answer 22

Pamelor

Question 23

What is the brand name of amitriptyline?

Answer 23

Elavil

Question 24

What is the brand name of imipramine?

Answer 24

Tofranil

Question 25

What is the brand name of desvenlafaxine

Answer 25

Pristiq

Question 26

What is the main SNDI?

Answer 26

mirtazapine

Question 27

What does SNDI stand for?

Answer 27

serotonin-norepinephrine disinhibitor

Question 28

What is the brand name of mirtazapine

Answer 28

Remeron

Question 29

What does MAOI stand for

Answer 29

Monoamine oxidase inhibitor

Question 30

What are the 4 main MAOIs

Answer 30

Isocarboxazid (Marplan) Phenelzine (Nardil) Selegiline (EMSAM) Tranylcypromine (Parnate)

Question 31

Brand name of isocarboxazid

Answer 31

Marplan

Question 32

Brand name of phenelzine

Answer 32

Nardil

Question 33

Brand name of selegiline

Answer 33

EMSAM

Question 34

Brand name of tranylcypromine

Answer 34

Parnate

Question 35

Not sure the class but what is the brand name of trazodone

Answer 35

Oleptro

Question 36

Which class of medication causes orthostatic hypertension due to the alpha one blocking which constricts cardiac muscle?

Answer 36

TCAs (MAOIs also cause Orthos)

Question 37

What class of drug blocks the breakdown of norepinephrine, dopamine, epinephrine, and serotonin in the synaptic terminals?

Answer 37

Monoamine oxidase an MAOI

Question 38

What tricyclic antidepressant is used for childhood enuresis or bedwetting

Answer 38

Clomipramine

Question 39

What three types of drugs can mimic depression

Answer 39

Oral contraceptives, levodopa, glucocorticoids

Question 40

Which diseases and deficiencies can cause depression

Answer 40

Vitamin B deficiency thyroid problem, Alzheimer’s disease, and maybe Hashimoto’s disease

Question 41

In addition to depression what else can antidepressants help with

Answer 41

Anxiety and pain

Question 42

What is the chemical name for serotonin

Answer 42

5-HT or 5-Hydroxytryptamine

Question 43

What does serotonin affect

Answer 43

There are high concentrations of serotonin in the hypothalamus, limbic system, the maDoula, and spinal cord.

Question 44

What body functions to serotonin control

Answer 44

NREM REM Pain perception, emotional states

Question 45

What enzyme terminates the action of norepinephrine in the synapse

Answer 45

``` There are two #1 MAO which is monamine oxidase #2 COMT =which is catecholamine o-methyltransferase ```

Question 46

What are the atypical antidepressants

Answer 46

``` Bupropion Duloxetine SNRI Mirtazapine Nefazodone Trazodone Venlafaxine. SNRI ```

Question 47

What is the brand name for venlafaxine?

Answer 47

Effexor

Question 48

What are the 10 tricyclic antidepressants or DCA’s?

Answer 48

``` Amitriptyline Amoxapine Clomipramine Desipramine Doxepin Imipramine Maprotiline Nortriptyline Protriptyline Trimipramime ```

Question 49

What drug besides gabapentin and Lyrica can be used to treat neuropathic pain

Answer 49

Cymbalta (duloxitine)

Question 50

What anti-depressant can lower the Seizure threshold?

Answer 50

Bupropion/Wellbutrin

Question 51

When do you use MAOIs?

Answer 51

After TCAs and SSRIs have failed

Question 52

MAOIs to grade a certain chemical in the intestines causing that chemical to enter the bloodstream and a high concentration displacing norepinephrine within the presynaptic nerve terminal. The sudden loss of norepinephrine causes acute hypertension. what is that chemical

Answer 52

Tyramine

Question 53

What are foods that contain tyramine

Answer 53

Avocados, bananas, raisins, papaya, figs, cheese, sour cream, yogurt, beer, red wine, liver, hearing, pepperoni, salami, sausage, hot dogs, baloney, yeast, chocolate, soy sauce, fava beans