Antidepressant meds Flashcards
Sertraline
(Zoloft)
SSRI
Tx:
MDD
PMDD
Panic Disorder
PTSD
OCD
off label: Social Anxiety Disorder
GAD
AE:
nausea
insomnia
somnolence
headache
dry mouth
sexual dysfunction
Pearls:
Be wary if initiating for anxiety (start lower)
safer in pregnancy/breastfeeding
Fluoxetine
(Prozac)
SSRI
Tx:
MDD
PMDD
Bulimia
Panic Disorder
OCD
off label: SAD, PTSD
AE:
Nausea
diarrhea
Sexual dysfunction
Pearls:
Be wary if initiating for anxiety
Citalopram
(Celexa)
SSRI
Tx:
MDD
PMDD
Panic disorder
PTSD
OCD
SAD
off label: GAD
AE:
nausea
diarrhea
sexual dysfunciton
dry mouth
headache
sweating
Pearls:
NOT recommended for pt with underlying cardiac dysfunction (can cause prolonged QTC)
Escitalopram
(Lexapro)
SSRI
Tx
MDD
GAD
PMDD
Panic disorder
PTSD
OCD
SAD
AE:
Nausea
diarrhea
sexual dysfunciton
weight gain
sedation
(usually well tolerated)
*BEST antidepressant for anxiety
_____________ is the best antidepressant for anxiety
Escitalopram (Lexapro)
Paroxetine
(Paxil)
SSRI
Tx:
MDD
OCD
Panic Disorder
SAD
PTSD
GAD
PMDD
AE:
Nausea
headache
somnolence-most sedating SSRI
dry mouth
sweating
weight gain
sexual dysfunction
Pearls:
Most sedating SSRi
May cause disocnintuation syndrome
Causes worst sexual dysfunction
___________ causes the worst sexual dysfunction
Paroxetine (Paxil)
Fluvoxamine
(Luvox)
SSRI
Tx:
OCD
SAD
GAD
PTSD
AE:
nausea
somnolence
asthenia
Buproprion
Wellbutrin
NDRI
Tx:
MDD
Seasonal Affective Disorder
Smoking Cessation
Sexual Dysfunction
AE:
weight loss
headaches
insomnia
agitation
dizziness
dry mouth
Pearls:
second line agent for ADHD
increased risk of seizures
Mirtazipine
(Remeron)
NaSSA
Tx:
MDD
GAD
Panic disorder
PTSD
AE:
weight gain
sedation
dry mouth
constipation
Pearls:
commonly used in elderly to promote sleep + weight gain
Venlafaxine
(Effexor)
SNRI
Tx:
MDD
GAD
SAD
Panic disorder
PTSD
AE:
nausea
headache
insomnia
diarrhea
Pearls: may cause hypertension
can help with anxiety
can cause horrible withdrawals
Desvenlafaxine
(Pristiq)
SNRI
Tx:
MDD
GAD
Panic disorder
PTSD
AE:
insomnia
anxiety
nausea
diarrhea
Duloxetine
(Cymbalta)
SNRI
Tx:
MDD
neuropathic pain
fibromyalgia
GAD
OCD
AE:
nausea
diarrhea
insomnia
sexual dysfunction
Pearl:
often used co-morbid neuropathic pain + depression
Amitriptyline
(Elavil)
TCA
Tx:
MDD
neuropathic pain
anxiety
headache
insomnia
AE:
nausea
blurred vision
weight gain
sedation
dry mouth
Pearls: if well tolerated, can be the most effective antidepressant on the market
*need to watch for cardiac events
Vilazodone
(Viibryd)
SSRI
Tx:
MDD
PMDD
Panic disorder
PTSD
OCD
SAD
GAD
AE:
nausea
diarrhea
sweating
dry mouth
headache
Pearls:
lower likelihood of weight gain/sexual side effects/sedation
Some insurances require several failed trials of SSRI/SNRI first
