Antidepressant Drug Names Flashcards
Imipramine
Tricyclic antidepressant
Fluoxetine
SSRI
(Prozac)
Longest 1/2 life w/ active metabolites. Do not need to taper.
Phenelzine
Monoamine Oxidase Inhibitor
Trimipramine
TCA
Citalopram
SSRI
Celexa
Amitriptyline
TCA
Paroxetine*
SSRI
(Paxil)
Most serotonin specific, most activating
Escitalopram*
SSRI
(Lexapro)
Fewer side effects, much more expensive
Desipramine*
TCA
Least sedating, least anticholinergic side effects
Clomipramine*
TCA
Most serotonin specific
Useful in treating OCD
Sertraline*
SSRI
(Zoloft)
highest risk for GI disturbances
Tranylcypromine
MAOI
Venlafaxine*
Serotonin/norepinephrine reuptake inhibitors (SNRI)
Useful in REFRACTORY DEPRESSION
Do not use w/ untreated/labile BP (increases BP)
Withdrawal symptoms: flu-like, electric like shocks/zaps
Bupropion*
Norepinephrine/dopamine reuptake inhibitors (NDRI)
(Wellbutrin)
SMOKING CESSATION, SAD, ADHD
+: No sexual side effects
-: Exacerbate psychosis (DA effect), lower seizure threshold
Nefazodone*
Serotonin antagonist/reuptake inhibitors (SARI)
REFACTORY MAJOR DEPRESSION
MD w/ ANXIETY
INSOMNIA
SE: nausea, dizziness, orthostatic hypotenison, *cardiac arrhythmias, *sedation, *priapism (erect penis)