Anticonvulsants Flashcards
What are seizures
Abnormal electrical activity in the brain causing sudden muscle contractions that happen without conscious control
How to anticonvulsants work
Decrease excitability or action potential of the brain
Reduce speed of nerve impulse conduction
Depress NS
What is the goal of treatment
Raise seizure threshold
Limit toxin effects
Maintain quality of life
Maintain compliance
Other uses for anticonvulsants
Migraines
Headaches
Psychiatric disorders
Neuropathic pain
Barbiturates
CNS depressant
Reduce RAS impulses
Slow nerve or muscle activity
Long a
Benzodiazepines
CNS depressant
Action unknown but acts on hypothalamus and limbo system
3 drugs approved for seizure drugs
Adverse rxns: hypotension and SOB
Hyantoin
Regulates sodium levels in motor synapses
Treatment of grand mall seizures, status epilepticus, neuralgia and migraines
Causes overgrown gums
Drugs included in hyantoin anticonvulsants
Phenytoin
Carbamazepine
Valorous acid
Succinamides
Interactions with bone marrow suppressants
GABA drugs
Depress electrical charges in the brain
Choice of drug may depend on type of seizure