Anticoagulation

Question 1

RAF Study.
Early Recurrence and Cerebral Bleeding in Patients with AIS and Afib.
Stroke. 2015.

Answer 1

Prospective.   Observational.  
N=1000
All pts had gotten TPA.  
Outcome:  CVA or TIA. Or bleed.  
About 75% ended up with anticoagulant.  

For CHADS2-VASC 4, 10% incidence primary outcome.
Pt should get a follow up CT 24 hours after TPA.
Best time to start anticoag: 4-14 Days after AIS.
Large lesion size may be better less irc