Anticoagulants Flashcards
1
Q
Tirofiban
Brand name
MOA. group
A
Aggrastat - IIB IIIA inhibitor
2
Q
Eptifibatide
- brand name
- MOA/Pharm group
A
Integrillin
Short-acting IIb / IIIa inhibitor
3
Q
Abciximab
brand name
MOA/ pharm group
A
Reopro
IIbIIIa inhibitor
4
Q
Prasugrel
Brand name
MOA
A
Effient
P2Y12 ADP receptor antagonist
5
Q
Aggrastat
generic name
A
Tirofiban
6
Q
Integrillin
generic name
MOA
A
eptifibatide
IIb/IIIa inhibitor
7
Q
when to stop tirofiban preoperatively
A
2-4 hours
8
Q
when to stop eptifibatide preoperatively
A
eptifibatide (integrillin) should be stopped 4-5 hours preoperatively
9
Q
When to stop abciximab preoperatively
A
(longer acting IIb IIIa inhibitor)
stop 12-24 hours before
10
Q
Lung penetration differences between beta-lactam and fluoroquinolone antibiotics
A
- Most beta-lactam antibiotics achieve less than 50% of their serum concentration in the lung.
- Fluoroquinolones and linezolid (an alternative to vancomycin) attain bronchial secretion concentrations equal or exceeding their serum concentrations
