Anticoagulants Flashcards

1
Q

Nommer un inhibiteur du facteur Xa

A

Xarelto (rivaroxaban)
Eliquis (apixaban)
Lixiana (edoxaban)

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2
Q

Le dabigatran (pradaxa) est un …

A

inhibiteur direct de la thrombine

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3
Q

Quand ajuster la dose de dabigatran ?

A

110 mg BID si ≥ 80 ans ou risque hémorragique élevé (≥75 ans et un facteur de risque)
CI en clairance ≤ 30

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4
Q

Quand ajuster le xarelto ?

A

Clairance entre 15 et 49 : Xarelto 15
CI en clairance ≤ 15

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5
Q

Quand ajuster l’éliquis ?

A

2 critères sur 3 : Poids ≤ 60 kg, créat ≥ 133, âge ≥ 80 ans
Peu de données en dialyse ou IRCT

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6
Q

Quand ajuster l’édoxaban ?

A

30 mg DIE
Clairance entre 30-49, poids < 60 kg ou prise Gp-p (verapamil, quinidine, dronédarone)
CI < 30 clairance

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7
Q

Antidote du dabigatran?

A

Idarucizumab

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8
Q

Antidote des anti Xa ?

A

andexanet alpha

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