Anticholinerestarase inhibitor - Donepezil Flashcards
1
Q
What is donepezil used for?
A
dementia:
- confusion
- memory
- awareness
2
Q
How does donepezil work?
A
Donepezil is a cholinesterase inhibitor. It works by increasing the amount of (acetylcholine) in the brain, which may help reduce the symptoms of dementia in patients with Alzheimer disease.
3
Q
What are the side effects of donepezil?
A
- GI upset
- loss of appetite / weight loss
- dizziness
- drowsiness
- weakness
- insomnia
- tremor
- QT prolongation (arrhythmias)
4
Q
What are the drug interactions of donepezil?
A
- apirin
- NSAIDs
- QT prolonging drugs e.g.
macrolides
quinine
quinolones
antipsychotics
tricyclic antidepressants
