Anticholenergic Drugs

Question 1

anticholinergic

Answer 1

drug that opposes the effects of acetylcholine at acetylcholine receptor sites

Question 2

belladonna

Answer 2

a plant that contains atropine as an alkaloid; used to dilate the pupils as a fashion statement in the past; used in herbal medicine much as atropine is used today

Question 3

cycloplegia

Answer 3

inability of the lens in the eye to accomodate to near vision, causing blurring and inability to see near objects

Question 4

mydriasis

Answer 4

relaxation of the muscles around the pupil, leading to pupil dilation

Question 5

parasympatholytic

Answer 5

lysing or preventing parasympathetic effects

Question 6

Therapeutic Actions

Answer 6

competitively block the acetylcholine receptors at muscarinic cholinergic receptor sites that are responsible for mediating effects of parasympathetic postganglionic impulses. Some are specific to certain receptors and others generally depress the parasympathetic system

Question 7

Indications

Answer 7

-decrease secretions prior to anesthesia
-to treat Parkinson’s
-to restore cardiac rate and BP after vagal stimulation during surgery
-relieve bradycardia
-relieve pylorospasm and hyperactive bowel
-to prevent motion sickness and vomiting
-relax biliary and ureteral colic
-relax bladder detrusor muscle and tighten sphincters
to control crying or laughing episodes in pts with brain injuries
-to relax uterine hypertonicity
-mgmt of peptic ulcer
-to control rhinorrhea associated with hay fever
-antidote for cholinergic drugs and for poisoning by certain mushrooms
-opthalmic agent to cause mydriasis or cycloplegia