Antibody Types & Effector Functions Flashcards by J Irc | Brainscape

Q

IgM & IgG

A

Trigger classical complement pathway

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Q

IgG

A

Binds to Fc receptors on cytolytic cells and triggers cytolysis of antibody coated cells through antibody-dependent cell-mediated cytotoxicity

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Q

IgA

A

Transported across epithelial surfaces and thus important for immunity at mucosal surfaces

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Q

IgE

A

Allergic responses; effective at triggering mast cell degranulation

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Q

IgG

A

Can cross placenta and thus important for protection of in utero and neonates

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