Antibody Testing in Autoimmune Disease Flashcards

1
Q

Anti-IgG/Rheumatoid factor

A
  • RA
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2
Q

Antinuclear Antibody (ANA)

A
  • SLE
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3
Q

Anti-dsDNA

A
  • SLE
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4
Q

Anti-sm (Anti Smith)

A

SLE

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5
Q

Anti-smooth muscle

A
  • Autoimmune hepatitis
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6
Q

Anti-histones

A
  • Drug induced lupus
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7
Q

Anti-centromere

A
  • Localized scleroderma (CREST)
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8
Q

Anti-topoisomerase I (Anti-Scl-70)

A
  • Scleroderma (systemic sclerosis)
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9
Q

Anti-mitochondrial

A
  • PBC
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10
Q

Anti-microsomal (Anti-peroxidase)

A
  • Hashimoto’s thyroiditis
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11
Q

Anti-thyroglobulin

A
  • Hashimoto’s thyroiditis
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12
Q

Anti-basement membrane

A
  • Goodpasture syndrome
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13
Q

Anti-epithelial (desmoglein 3)

A
  • Pemphigus vulgaris
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14
Q

Anti-epithelial (hemidesmosome)

A
  • Bullous pemphigoid
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15
Q

Anti-gliadin

A
  • Celiac sprue
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16
Q

Anti-Jo-1

A
  • Myositis/dermatomyositis
17
Q

Anti-SS-A (Anti-Ro)

A
  • Sjogren’s syndrome
18
Q

Anti-SS-B (Anti-La)

A
  • Sjogren’s syndrome
19
Q

Anti-U1-RNP (Ribonucleoprotein)

A

Mixed CTD

20
Q

Anti-glutamate decarboxylase

A
  • Type-1 diabetes
21
Q

Anti-parietal cell

A
  • Pernicious anaemia
22
Q

c-ANCA

A

-Wegner granulomatousus

23
Q

p-ANCA

A

Microscopic polyangitis and Churg-Strauss (EGPA)