Antibody & Disease Association Flashcards

1
Q

RF

A

Rheumatic Disease

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2
Q

CCP

A

RA (Sensitive + Specific)

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3
Q

ANA / FANA

A

SLE (Sensitive), Sjogren, Myositis, Lupus,

Old Age, + FMHx

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4
Q

ACH

A

Sjogren

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5
Q

Sc70 / Topo

A

Diffuse Scleroderma (Specific + Sensitive)

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6
Q

Centromere

A

CREST (Specific + Sensitive)

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7
Q

RNA-Poly 3

A

Scleroderma Renal Crisis

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8
Q

Th

A

Scleroderma PAH

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9
Q

PM-Sci

A

Systemic Scleroderma, Polymyositis

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10
Q

PDGF-R

A

Scleroderma

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11
Q

MMP

A

Scleroderma

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12
Q

Histone

A

Rx-SLE

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13
Q

Ro/SSA (ENA)

A

Sjogren, SLE (Neonatal, SCLE)

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14
Q

La/SSB (ENA)

A

Sjogren, SLE (Neonatal)

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15
Q

Sm

A

SLE (Specific, but not equal to Disease Activity)

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16
Q

U1RNP

A

MCTD (mixed connective tissue disease)

17
Q

ds-DNA

A

Renal SLE (Equal to Disease Activity)

18
Q

Jo1 / Synthetase

A

Inflammatory Myopathy (Synthetase Syndrome)

19
Q

SRP

A

Inflammatory Myopathy ( Decrease Prog)

20
Q

Mi-2

A

Inflammatory Myopathy (Increase Prog)

21
Q

P-Lipid (LA/aCL)

A

HyperCoag anticardiolipin antibodies = aCL

SLE (Miscarriage, Neuro) lupus anticoagulant = LA

22
Q

cANCA

A

Granulomatosis with polyangiitis

Wegener’s

23
Q

pANCA

A

Micro. Polyangitis, Churg-Strauss, IBD

24
Q

Serial ESR/CRP

A

RA