Antibodies / Autoimmune Flashcards
Anti-Slc-70
(Anti-dna topoisomerase)
Scleroderma
Systemic sclerosis w interstitial lung disease
AMA
(Antimitochondrial)
Primary biliary cirrhosis
PBC
Anti-ro, anti-la
Sjorgen,
What mutation to look for in
Splanchnic vein thrombosis
JAK2 tyrosine kinase mutation
Anti-RNA polymerase III antibody
Renal crisis in systemic sclerosis
What condition is this:
Petichea, ecchymosis, thrombocytopenia
NO lymphadenopathy or splenomegaly
ITP
Immune thrombocytopenic purpura
Treatment for ITP
moderate: glucocorticoid if plat <30k
Life threatening: IV IG
Treatment for TTP
Plasma exchange
To remove von willabrand factor and replace deficient ADAMTS13
Are PRURITIC blister disorder with FLACCID, oral or other mucosal bullae that rupture and leave erotions.
Nikolsky positive
Pemphigus vulgaris
Anca associated vasculitis
Granulomatosis w polyangiitis
Microscopic polyangiitis
Eosinophilic granulomatosis w polyangiitis
Daily evening, fevers, salmon – rash, inflammatory, arthritis, sore throat, serositis, inflammatory markers, elevation, elevated ferritin
WHAT IS THIS
adult onset still disease
Parkinson plus syndrome with symmetric parkinsonism, severe dysautonomia, orthostatic, hypertension, urinary incontinence, cellular, ataxia, early falls
Multiple system atrophy
Parkinson – plus syndrome. Symmetric Parkinson, ism, postural instability, early falls, vertical oculomotor deficit.
Progressive supranuclear palsy
Maintenance treatment for Ulcerative Colitis
Infliximab or adalimumab
bleeding too much. what leukemia?
Acute promyelocytic leukemia
(ApML)
(high nucleus to cytoplasm ration. packed aur rods on red arrow, violet granules on cytoplasm)
