Antibodies Flashcards
AntiCCP
Rheumatoid Arthritis
SLE antibodies
Most specific: Anti-dsDNA
Most sensitive: ANA
Antiphospholipid syndrome
Anti-Cardiolipin
Lupus antibody
Sjogren’s
Anti-RO
Ant- La
Systemic Sclerosis
Limited: Anti-centromere
Diffuse: Anti SCL70
Polymyositis
Dermatomyositis
Anti- Jo (?mainly polymyositis)
Anti-Mi2 (? mainly dermatomyositis)
pANCA
Eosinophillic granulamtous polyangitis / Churg-Strauss
Microscopic Polyangitis
?Primary sclerosing cholangitis
cANCA
Wegner’s / Granulamtous with polyangitis
Primary Biliary Cholangitis
Antimitochondrial antibodies
Primary Sclerosing Cholangitis
ANCA
Autoimmune Hepatitis
Depends on type
ANA
Anti-smooth muscle
Pernicious Anaemia
Anti- intrinsic factor
Anti-parietal cells
Hashimoto’s Thyroiditis
Anti-TPO
Graves
Anti-TSH receptor