Antibodies Flashcards
1
Q
Rules out SLE
A
ANA
2
Q
Most sensitive for SLE
A
Anti-ds DNA or anti-Smith
3
Q
Drug induced lupus (e.g. hydralazine)
A
Anti-histone
4
Q
Sjogren’s
A
anti-Ro (SSA), anti-La (SSB) [also seen in other dz]
5
Q
CREST syndrome
A
anti-centromere
6
Q
Systemic sclerosis
A
anti-topoisomerase, anti-Scl-70
7
Q
Mixed CTD
A
Anti-RNP
8
Q
RA
A
RF (IgM against Fc of IgG), anti-CCP
9
Q
Type 1 hypersensitivity reaction
A
IgE mediated eg anaphylaxis
10
Q
Type 2 hypersensitivity run
A
IgG or IgM and cytotoxic cell mediated, such as Goodpastures, pemphigus vulgaris
11
Q
Type 3 hypersensitivity rxn
A
Immune complex mediated such as lupus
12
Q
Type 4 hypersensitivity rxn
A
T cell mediated, delayed hypersensitivity, such as transplant rejection, allergic contact dermatitis
