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Phase 3a > Antibodies > Flashcards

Antibodies Flashcards

MSK (RA, SLE, dermamyositis, sjorgens etc), IBD antibodies, there are probably others

1
Q

How can ulcerative colitis and Crohn’s be differentiated using an antibody test?

A

UC = pANCA +ve
Crohn’s = pANCA -ve

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2
Q

2 antibodies are present in rheumatoid arthritis. One is specific, one is non-specific. Name them.

A

Specific = anti-CCP
Non-specific = Rheumatoid factor

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3
Q

Systemic lupus erythematosus

A

ANA antibodies (99% of cases)
Anti dsDNA antibodies (used to monitor progression)

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4
Q

Antiphospholipid syndrome

A

Anticardiolipin antibodies
Anti B2 glycoprotein-1 antibodies

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5
Q

Sjogren syndrome

A

Anti-Ro antibodies
Anti-La antibodies
ANA often positive

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6
Q

Scleroderma

A

Anti centromere antibodies (ACAs) positive in 70% of cases
ANA often positive

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7
Q

How do the antibodies of polymyositis and dermatomyositis differ?

A

Polymyositis = Anti Jo1
Dermatomyositis = Anti Jo1 + anti Mi2

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8
Q

Fibromyalgia

A

No serological markers

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9
Q
A
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Phase 3a (6 decks)

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