Antibiotics that Inhibit Prokaryotic (Bacterial) Transcription or Translation Flashcards

1
Q

Tetracyclines

A

TRANSLATION
- binds 30S ribosomal subunit
- -> inhibits aminoacetyl + RNA attachment

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2
Q

Aminoglycosides

A

TRANSLATION
- binds 30S ribosomal subunit
–> inhibit complex formation

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3
Q

Chloramphenical Clindamycin

A

TRANSLATION
- inhibits 50S peptide-trasnferase
–> inhibit peptide bond formation during elongation

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4
Q

Macrolide

A

TRANSLATION
- block translocation step of elongation

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5
Q

Rifampicin

A

TRANSCRIPTION
- inhibits bacterial RNA polymerase
*used for Tuberculosis

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