Antibiotics for Interns

Question 1

Which antibiotics would be used for severe CAP? What dose? For how long?

Answer 1

Cetriaxone 1g IV daily

Azithromycin 500 IV daily

Continue for 2-3d, until clinically stable

Then replace with oral for a week

Question 2

What is the SaO2 target for someone with COPD?

Answer 2

>92%

Question 3

What is ipatropium?

Answer 3

A short acting anti-cholinergic

Question 4

What medical management of airways is required for an infective exascerbation of COPD?

Answer 4

SABA - Salbutamol

Short acting anti-cholinergic - Ipatropium

Question 5

What must you be wary of when differentiating pneumonia from infective exascerbation of COPD?

Answer 5

Consolidation on CXR might not have shown itself

Question 6

What are the first line therapy for IECOPD?

Answer 6

Doxycycline 200mg PO stat then 100mg PO daily

Question 7

Is doxycycline bacteriocidal or static?

Answer 7

Static

Question 8

What are some side effects of doxycycline?

Answer 8

Tooth discolouration

Photo sensitivity

Question 9

What is the ideal number of blood cultures to take?

Answer 9

3

Question 10

What are the empirical antibiotics for peritonitis?

Answer 10

Piperacillin and tazobactam

or

Ampicillin 2g IV q6hr (covers enterococcus)

Metronidazole 500mg IV q12hr

Gentamicin

Question 11

What is a side effect of prolonged piperacillin use?

Answer 11

Liver damage

Question 12

What is a solid oral, broad spectrum antibiotic?

Answer 12

Augmentin duofort

Question 13

What is the standard abx for cellulitis?

Answer 13

Flucloxicillin

(vancomycin if allergic to penicillins)

Question 14

What is clindamycin good for?

Answer 14

Gram positives in penicillin allergic patients