Antibiotics - Fitzpatrick Flashcards
Beta-lactam antibiotics have what general function?
Cell wall synthesis inhibition
Glycopeptide antibiotics have what general function?
Cell wall synthesis inhibition
Beta-lactam antibiotic classes (4)
- Penicillins
- Cephalosporins
- Monobactams
- Carbapenems
Glycopeptide antibiotic drug (1)
Vancomycin
30S ribosome (protein synthesis) inhibitor drug classes (2)
- Aminoglycosides
- Tetracyclines
50S ribosome (protein synthesis) inhibitor drug classes (5)
- Macrolides
- Chloramphenicol
- Clindamycin
- Oxazolidinones
- Quinpristin/Dalfopristin
Folate synthesis inhibitor antibiotic classes (2)
- Sulfonamides
- Anti-folates
Nucleic Acid Disruption antibiotic classes (2)
- Fluoroquinolones
- Rifamycins
BacterioSTATIC antibiotic groups (2)
- Folate synthesis inhibitors
- Ribosome inhibitors (except aminoglycosides)
BacterioCIDAL antibiotic groups (3)
- Cell wall inhibitors
- Nucleic acid disruptors
- Aminoglycosides (30S)
If a patient is immunocompromised, would you prefer a bacteriostatic or bacteriocidal antibiotic?
BacterioCIDAL (will kill organisms regardless of immune system)
Prophylaxis for anthrax
Ciprofloxacin or doxycycine
Prophylaxis for HIV
Tenofovir/emtricitabine + raltegravir
Prophylaxis for Influenza A and B
Oseltamivir
Prophylaxis for meningococcemia
Rifampin, Cipro, or Ceftriaxone
Prophylaxis for PCP
Trimethoprim-sulfamethoxazole, dapsone, or atovaquone
Prophylaxis for Toxo
Trimethoprim-sulfamethoxazole
Prophylaxis for H. influenzae
Rifampin
Penicillin adverse effect
Hypersensitivity
Cephalosporin adverse effect
Hypersensitivity
Aminoglycosides adverse effects
Nephrotoxicity, Ototoxicity (balance or hearing)
Tetracyclines adverse effects
Deposition in bone
Fluoroquinolones adverse effect
Cartilage/tendon damage
Drugs with most selective toxicity
Bacterial drugs
