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Respiratory 2 > Antibiotics - Fitzpatrick > Flashcards

Antibiotics - Fitzpatrick Flashcards

1
Q

Beta-lactam antibiotics have what general function?

A

Cell wall synthesis inhibition

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2
Q

Glycopeptide antibiotics have what general function?

A

Cell wall synthesis inhibition

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3
Q

Beta-lactam antibiotic classes (4)

A
  • Penicillins
  • Cephalosporins
  • Monobactams
  • Carbapenems
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4
Q

Glycopeptide antibiotic drug (1)

A

Vancomycin

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5
Q

30S ribosome (protein synthesis) inhibitor drug classes (2)

A
  • Aminoglycosides

- Tetracyclines

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6
Q

50S ribosome (protein synthesis) inhibitor drug classes (5)

A
  • Macrolides
  • Chloramphenicol
  • Clindamycin
  • Oxazolidinones
  • Quinpristin/Dalfopristin
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7
Q

Folate synthesis inhibitor antibiotic classes (2)

A
  • Sulfonamides

- Anti-folates

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8
Q

Nucleic Acid Disruption antibiotic classes (2)

A
  • Fluoroquinolones

- Rifamycins

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9
Q

BacterioSTATIC antibiotic groups (2)

A
  • Folate synthesis inhibitors

- Ribosome inhibitors (except aminoglycosides)

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10
Q

BacterioCIDAL antibiotic groups (3)

A
  • Cell wall inhibitors
  • Nucleic acid disruptors
  • Aminoglycosides (30S)
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11
Q

If a patient is immunocompromised, would you prefer a bacteriostatic or bacteriocidal antibiotic?

A

BacterioCIDAL (will kill organisms regardless of immune system)

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12
Q

Prophylaxis for anthrax

A

Ciprofloxacin or doxycycine

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13
Q

Prophylaxis for HIV

A

Tenofovir/emtricitabine + raltegravir

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14
Q

Prophylaxis for Influenza A and B

A

Oseltamivir

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15
Q

Prophylaxis for meningococcemia

A

Rifampin, Cipro, or Ceftriaxone

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16
Q

Prophylaxis for PCP

A

Trimethoprim-sulfamethoxazole, dapsone, or atovaquone

17
Q

Prophylaxis for Toxo

A

Trimethoprim-sulfamethoxazole

18
Q

Prophylaxis for H. influenzae

A

Rifampin

19
Q

Penicillin adverse effect

A

Hypersensitivity

20
Q

Cephalosporin adverse effect

A

Hypersensitivity

21
Q

Aminoglycosides adverse effects

A

Nephrotoxicity, Ototoxicity (balance or hearing)

22
Q

Tetracyclines adverse effects

A

Deposition in bone

23
Q

Fluoroquinolones adverse effect

A

Cartilage/tendon damage

24
Q

Drugs with most selective toxicity

A

Bacterial drugs

25
Q

Drugs with least selective toxicity

A

Cancer and viral drugs

26
Q

When are bacterioCIDAL agents preferred?

A
  • Immunocompromised

- SEVERE infections

Respiratory 2 (15 decks)

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